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Review ArticleMechanisms of Disease

Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs

List of authors.
  • Turk Rhen, Ph.D.,
  • and John A. Cidlowski, Ph.D.

Glucocorticoids are among the most common therapeutic agents used in medical practice, yet their mechanisms of action are only partly understood. This review summarizes our understanding of how glucocorticoids inhibit inflammation and give rise to side effects.

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Author Affiliations

From the Department of Biology, University of North Dakota, Grand Forks (T.R.); the Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, N.C. (J.A.C.); and the Department of Health and Human Services, National Institutes of Health, Bethesda, Md. (J.A.C.).

Address reprint requests to Dr. Cidlowski at the Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, 111 T.W. Alexander Dr., Research Triangle Park, NC 27709, or at [email protected].

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